Comparison of the Effects of Quadriceps and Gastrocnemius Muscle Training on Activities of Daily Living in COPD
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- 6 Minute Walk Test (6 MWT):
研究概览
简要总结
Chronic obstructive pulmonary disease (COPD) contributes significantly to global morbidity and mortality; It is a disease that affects an estimated 210 million people worldwide and is the third most common cause of death. COPD is identified by persistent airflow limitation and is associated with progressively worsening lung function, dyspnea, health-related quality of life (HRQOL), and impaired exercise capacity. Poor exercise capacity is a common finding of chronic obstructive pulmonary disease (COPD). Central cardiopulmonary factors, respiratory muscle dysfunction, gas exchange abnormalities, and skeletal muscle dysfunction all play a role in limiting exercise capacity The aim of this study is to investigate the effects of neuromuscular electrical stimulation applied to different muscle groups (quadriceps femoris and gastrocnemius muscles) on exercise performance and quality of life in patients with stable COPD and compare it with standard treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Being between 18-75 years old,
- •Diagnosed as group B stable COPD according to GOLD criteria by a pulmonologist,
- •PaO2 >55 mm Hg, PaCO2 <45 mmHg in room air.
排除标准
- •Exacerbation,
- •Cor pulmonale or respiratory muscle fatigue (abdominal paradoxical breathing),
- •Cardiac instability (with acute MI, congestive heart failure, or uncontrollable arrhythmia),
- •Musculoskeletal disorder (conditions affecting exercise ability),
- •Difficulty communicating.
结局指标
主要结局
6 Minute Walk Test (6 MWT):
时间窗: 4 weeks
they could walk for 6 minutes, according to heart rate, blood pressure, respiratory rate, finger oxygen saturation, the walking distance at the end of walking, and dyspnea score according to the Modified Borg Scale (MBS) at the beginning and end of walking was recorded. Change from baseline 6 Minute walking performance after 4 weeks will be examined.
次要结局
- St. George's Respiratory Questionnaire (SGRQ):(4 weeks)
- Modified Borg Scale (MBS):(4 weeks)
- Beck Depression Inventory (BDI):(4 weeks)
研究者
Ahmet Payas
Director
Hitit University