Prediction of Uterine Atony After Vaginal Delivery by Shear Wave Elastography: a Feasibility Study
Overview
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Stiffness of the myometrium
Overview
Brief Summary
Prospective study evaluating the feasibility of shear-wave elastography of the uterus during the third stage of labour and following placental delivery. The investigators hypothesize that the stiffness of the myometrium can be measured by using shear-wave technology. This study involves 30 patients with a healthy pregnancy and spontaneous vaginal delivery. One co-investigator will carry out measurements at the uterine fundus, at three different time points: after fetal delivery, after placental delivery and 30 minutes after placental delivery.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •singleton pregnancy
- •cephalic presentation
- •maternal age \> 18 years old
- •nulliparous
- •healthy uncomplicated pregnancy
- •gestational age between 37-42 weeks of gestation
- •spontaneous labour and delivery
- •uncomplicated progression of labour (cervical dilatation at \>1 cm/h)
- •administration of less than 3 units of oxytocin during the second stage of labour
- •patient having read, accepted and signed the consent form
Exclusion Criteria
- •antepartum hemorrhage in the present pregnancy
- •protracted second stage of labour (more than two hours from full dilatation to delivery)
- •more than 30 minutes of active pushing
- •BMI \> 35 kg/m2
- •distance from skin to uterus \> 8 cm
- •age \> 35 years old
- •instrumental deliveries
- •bleeding disorders
- •polyhydramnios
- •pre-eclampsia
Outcomes
Primary Outcomes
Stiffness of the myometrium
Time Frame: Third labor stage to 30 minutes post placenta delivery
Difference in median myometrial shear wave velocity between each time point: after fetal delivery, after placental delivery and 30 minutes after placental delivery.
Secondary Outcomes
- Blood loss(Two hours following the childbirth)
Investigators
DAVID DESSEAUVE
Principal investigator
Centre Hospitalier Universitaire Vaudois