Deciphering the association between iron homeostasis and ovarian function in polycystic ovarian syndrome - PCOS

Manipal Academy of Higher Education0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年10月16日

试验速览

暂无简介。

•Control group: Infertile women attending the infertility clinic will be recruited for the study.
•Women with male factor infertility, normal BMI = 25kg/m2
•, regular menstrual
•cycles and no clinical signs of hyperandrogenism will be considered as control population.
•Obese group: Women with high BMI > 25kg/m2 and no clinical signs of
•hyperandrogenism will be considered under obese, non-PCOS group.
•PCOS group: Women with PCOS pattern (with metformin and without metformin
•treatment) will be included in the study. For PCOS group, women diagnosed
•with PCOS based on the Rotterdam criteria and undergo ovary stimulation will be selected. In
•addition, women with Type 2 diabetes will be included in this study group.
•PCOS + Metformin group: For PCOS with metformin group, women diagnosed
•with PCOS and Type 2 diabetes, undergoing metformin treatment for at least one month will be

•Women with chronic cardiovascular disease, chronic kidney disease,
•diabetes, thyroid disease, and pulmonary disease will be excluded from the study. In addition,
•women using sex-steroids, women who had ovarian surgery in the past, women with
•premature ovarian failure and women who had chemotherapy in the past will be excluded.

发起方