Collaborative Optical Macular Pigment ASsessment Study

Not Applicable

Completed

• Conditions: Enhancing vision performance and comfort; Eye Diseases; Vision performance

• Registration Number: ISRCTN35481392
• Lead Sponsor: Enterprise Ireland (Ireland)

Brief Summary

2011 results in: https://www.ncbi.nlm.nih.gov/pubmed/21237188 (added 11/06/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-07-24
• Study Completion: 2009-03-31
• Last Update Posted: 1 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 121

Inclusion Criteria

1. Any race
2. Male or female
3. Aged 18 to 40 years
4. No presence of ocular pathology
5. Visual acuity of at least 6/18 in the study eye

Exclusion Criteria

1. Outside age range 18 to 40
2. Pregnancy
3. Presence of ocular pathology
4. Cataract

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. To determine whether a person's macular pigment optical density relates to visual performance and/or ocular comfort, measured using heterochromatic flicker photometry<br> 2. To determine whether augmentation (through supplementation) of a person's macular pigment optical density results in enhanced visual performance and/or improved ocular comfort, measured via questionnaire and by a variety of objective vision assessment techniques<br><br> The primary and secondary outcome measures will be assessed at each study visit.<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. To determine whether changes in serum concentrations of lutein and zeaxanthin are associated with changes in macular pigment levels in normal subjects<br> 2. To determine whether objective assessments of visual performance are associated with subjective, questionnaire based, assessments of visual performance<br><br> The primary and secondary outcome measures will be assessed at each study visit.<br>