Efficacy and security of low toxicity immunosuppressive regimen using basiliximab, mycophenolate mofetil, neoral or tacrolimus and corticosteroids versus full doses of neoral, thymoglobulin, azathioprine and corticosteroids
Completed
- Conditions
- Kidney transplantUrological and Genital Diseases
- Registration Number
- ISRCTN87678078
- Lead Sponsor
- Hospital Universitario de Canarias (Spain)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 240
Inclusion Criteria
1. Aged over 18 years
2. Accepted informed consent
3. Primary kidney allograft
4. Cadaveric donor
Exclusion Criteria
1. Panel Reactive Antibody (PRA) over 50%
2. History of malignancy
3. History of infection
4. Previous treatment with polyclonal antibodies or basiliximab
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine renal function evaluated by calculated creatinine clearance at 6 and 12 months.<br>
- Secondary Outcome Measures
Name Time Method To assess acute rejection rate at 6 and 12 months, patient and graft survival rate at 12 months.