Quantification of bowel motility in gynecological cancer patients during radiotherapy using MRI.

Completed

• Conditions: Bowel motility; 10038594

• Registration Number: NL-OMON48630
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

* age >18 years
* Treatment plan: Definitive radiotherapy with curative intent ± chemotherapy
or hyperthermia
* Tumor type and stage:
- Cervical carcinoma (FIGO IB-IVA).
- Vaginal carcinoma (FIGO I-IVA).
- Isolated vaginal recurrence of endometrial carcinoma.
* Written informed consent

Exclusion Criteria

* Claustrophobia
* Any 3T MRI contra-indications stated by the AMC MRI safety committee (See
protocol appendix A)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter of the study is to quantify bowel motility in three<br /><br>orthogonal directions in gynecological cancer patients treated with definitive<br /><br>radiotherapy using MRI.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameters/endpoints are :<br /><br><br /><br>- assessment of bowel motility variation within a patient during their<br /><br>treatment course.<br /><br>- assessment of bowel motility variation between patients with a focus on<br /><br>changes of bowel motility associated with major abdominal surgery.</p><br>