EFFECT OF GUDUCHI RASAKRIYA ANJANAM IN IMMATURE SENILE CATARACT A PRE POST INTERVENTIONAL STUDY
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Visual acuity assessed by log MAR visual acuity chart
研究概览
简要总结
The term cataract refers to development of any opacity in the lens or its capsule. Age related cataract or senile cataract is the most common type of acquired cataract. The symptoms include glare, coloured halos, black spots in front of eyes, distorted images and gradually progressive loss of vision. In modern medicine treatment of cataract essentially consists of its surgical removal.[1]These symptoms resemble Kaphaja kacha in Ayurveda.Guduchi Rasakriya Anjanam is indicated in timira and kacha chikitsa. Triphala is advised to be taken with ghritham in timira chikitsa.This pre and post-interventional study aims to assess the combined effect of Guduchi rasakriya anjanam twice daily and internal use of 5gm Triphala choornam with ghritham for 21 days in 33 subjects aged 50- 75 years with immature senile cataract attending the Out Patient Department of Shalakyatantra, Government Ayurveda College Hospital, Kannur in reducing symptoms like glare and floaters and improving visual acuity, contrast sensitivity and LOCSIII grading of cataract. Assessment will be done before and after Poorvakarma, on the 1st day of intervention, on 22nd day after the intervention and on the Follow up after a gap of 15 days. Results will be statistically analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 50.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects diagnosed as IMSC based on symptoms such as floaters and glare, presence of iris shadow and diagnosed as immature senile cataract as per LOCSIII criteria .
- •Subjects willing to provide informed consent.
排除标准
- •Subjects who are contra indicated for anjana karma.
- •Subjects with diabetes mellitus.
- •Subjects with inflammatory and infective diseases of eye ball and its appendages.
- •Subjects who are under steroid medication for past 1 month.
- •Subjects with any other ocular pathology that causes diminished vision.
- •Subjects with visual acuity greater than 0.3 on log MAR scale.
- •Subjects with a score less than 1.0 log units in Pelli Robson contrast sensitivity scale.
结局指标
主要结局
Visual acuity assessed by log MAR visual acuity chart
时间窗: Assessment will be done on 0 th day, 8 th day, 22nd day, 30th day, 45th day
Contrast sensitivity assessed by Pelli Robson contrast sensitivity chart
时间窗: Assessment will be done on 0 th day, 8 th day, 22nd day, 30th day, 45th day
Change in grade of cataract assessed by LOCSIII.
时间窗: Assessment will be done on 0 th day, 8 th day, 22nd day, 30th day, 45th day
次要结局
未报告次要终点
研究者
Dr Sneha Nair
Government Ayurveda College Kannur