Multi Detector-Row Computed Tomography (MDCT) Calcium Score of Heart Transplanted Patients

Not Applicable

Completed

• Conditions: Coronary Artery Disease

• Registration Number: NCT00294853
• Lead Sponsor: Oslo University Hospital

Brief Summary

The purpose of the study is to determine if calcium score can be used as a predictor of coronary artery disease in heart transplanted patients, as it is used in non-transplanted persons.

Detailed Description

Several studies have shown that a negative calcium score is a strong independent negative predictor of coronary artery disease (CAD). CAD in heart transplants (HTx) differs from CAD lesions in native hearts. The aim of this study is to see if there is a similar relation between coronary artery calcium and CAD in transplanted hearts as in native hearts.

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2006-02-21
• Study First Submitted QC: 2006-02-21
• Study First Posted: 2006-02-22
• Study Completion: 2007-06
• Status Verified: 2008-04
• Last Update Submitted: 2011-07-03
• Last Update Posted: 2011-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

• Heart transplanted patient
• Aged 18 or above.

Exclusion Criteria

• Pregnancy
• Atrial fibrillation
• Severe heart failure New York Heart Association (NYHA) class IV
• Severe pulmonary disease making the patient unable to hold his/her breath for more than 10 seconds.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Calcium score	at the date of examination

Secondary Outcome Measures

Name	Time	Method
Coronary stenoses found on coronary angiography	at the date of examination

Trial Locations

Locations (1)

Rikshospitalet-Radiumhospitalet HF; 🇳🇴 Oslo, Norway