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Post-Market Clinical Follow-up Study of A-SPINE's Products

Conditions
Kyphosis
Trauma
Scoliosis
Degenerative Disc Disease
Deformity
Tumor
Stenosis
Pseudoarthrosis of Spine
Interventions
Device: (1) SmartLoc (2) SmartLoc Evo (3) Winloc(4) Vigor PEEK Cervical Disc Spacer (5) Combo C (6) Polymer Lumbar Disc Spacer (7) X'Plo (8) Rainboo (9) Combo L
Registration Number
NCT04848376
Lead Sponsor
A-Spine Asia Co., Ltd.
Brief Summary

This is a post-market clinical follow-up study that use questionnaires such as Visual Analog Scale (VAS), the Neck Disability Index (NDI), or the Oswestry Disability Index (ODI) to compare the clinical improvement effects before and after surgery.

Detailed Description

The purpose of study is to confirm the safety and and performance of the A-SPINE's products for using 2 years. This post-market clinical follow-up study use questionnaires such as Visual Analog Scale (VAS), the Neck Disability Index (NDI), or the Oswestry Disability Index (ODI) to evaluate the clinical improvement effects. Subjects will be evaluated at pre-operation, 6 months, 12 months, and 2 years post treatment. Finally, analyze the clinical outcome, fusion rate, and adverse events.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Subject is above 20 years of age;
  • Subject is indicated for A-SPINE Spinal Fixation System;
  • Subject is willing and able to provide informed consent to participate in the study;
  • Subject is willing and able to understand the purpose of the study, his/her role, and is available to return to the clinic/hospital for all required follow-up visits.
Exclusion Criteria
  • Subjects will be excluded if, in the opinion of the Investigator, the subject does not qualify based on approved labeling requirements or Subject Inclusion Criteria.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Spine surgery(1) SmartLoc (2) SmartLoc Evo (3) Winloc(4) Vigor PEEK Cervical Disc Spacer (5) Combo C (6) Polymer Lumbar Disc Spacer (7) X'Plo (8) Rainboo (9) Combo LUse these system: (1) SmartLoc (2) SmartLoc Evo(3) Winloc (4) Vigor PEEK Cervical Disc Spacer (5) Combo C (6) Polymer Lumbar Disc Spacer (7) X'Plo (8) Rainboo (9) Combo L
Primary Outcome Measures
NameTimeMethod
Visual Analogue Scale- Change from baseline at 2 yearChange from baseline at 2 year

Visual Analogue Scale is a patient-reported outcome measure. The scale ranges from 0 to 10. A score of 0 represents no pain, while a score of 10 represents extreme pain. Compare baseline and postoperative improvement VAS scores.

Secondary Outcome Measures
NameTimeMethod
Number of Device-related Adverse EventsBaseline, 6 months,12 months, 24 months

Adverse events associated with the device will be assessed at each follow-up visit and the number of cases at the 2-year follow-up will be counted.

Oswestry Disability IndexBaseline, 6 months,12 months, 24 months

The ODI is a questionnaire that is commonly used in clinical trials to measure the self-reported functional status of patients with neck pain.The ten questions are measured on a 6-point scale from 0 (no disability) to 5 (full disability). Compare baseline and postoperative improvement ODI scores.

Fusion RateBaseline, 6 months,12 months, 24 months

Use X-ray or CT to detect the spine fusion.

Neck Disability IndexBaseline, 6 months, 12 months, 24 months

The NDI is a questionnaire that is commonly used in clinical trials to measure the self-reported functional status of patients with neck pain.The ten questions are measured on a 6-point scale from 0 (no disability) to 5 (full disability). Compare baseline and postoperative improvement NDI scores.

Trial Locations

Locations (1)

Taichung Tzu Chi Hospital

🇨🇳

Taichung, Taiwan

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