跳至主要内容
临床试验/NCT03133182
NCT03133182已完成不适用

Association of Polypharmacy With Outcomes After Elective Noncardiac Surgery: a Population-based Cohort Study

Ottawa Hospital Research Institute0 个研究点目标入组 266,499 人开始时间: 2002年4月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
266,499
主要终点
Mortality

研究概览

简要总结

This study investigates the association of preoperative polypharmacy with outcomes and healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

详细描述

Multilevel multivariable regression analysis will be used to investigate the adjusted association between preoperative polypharmacy and postoperative outcomes and healthcare resource utilization. Sensitivity analyses will be used to evaluate the robustness of the primary analysis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Intermediate to high risk elective non-cardiac surgery
  • Age >=66 on day of surgery

排除标准

  • 未提供

研究组 & 干预措施

Polypharmacy

People taking >=5 unique prescription drugs in the 3 months prior to surgery

干预措施: Polypharmacy (Drug)

结局指标

主要结局

Mortality

时间窗: from day of surgery up to 90 days after surgery

death from any cause

次要结局

  • Complications(From day of surgery to day of hospital discharge, up to 365 days after surgery)
  • Institutional Discharge(date of surgery to date of hospital discharge, or 365 days after surgery, whichever comes first)
  • Length of Stay(date of surgery to date of hospital discharge, or 365 days after surgery, whichever comes first)
  • Costs of Care(date of surgery up to 90 days after surgery)
  • Hospital Readmission(From the date of hospital discharge to 30 days after the date of discharge)

研究者

申办方类型
Other
责任方
Sponsor

相似试验

Polypharmacy and Outcomes After Elective Noncardiac... | 临床试验