JPRN-jRCT1031220336
Recruiting
Phase 2
Effects of pharmacological treatments on hemodynamics, cardiovascular reserve, exercise tolerance, and prognosis in heart failure with preserved ejection fraction - Effects of pharmacological treatments on hemodynamics, cardiovascular reserve, exercise tolerance, and prognosis in heart failure with preserved ejection fraction
Obokata Masaru0 sites125 target enrollmentSeptember 14, 2022
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Heart failure with preserved ejection fraction
- Sponsor
- Obokata Masaru
- Enrollment
- 125
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Age equal to or more than 20 years old
- •2\) Patients with EF of 50% or more than 50%
- •3\) Patients with established HFpEF or subjects who are suspected of HFpEF
- •4\) Patients with possible new initiation of medications such as empagliflozin, sacubitril valsartan, or spironolactone.
- •5\) Patients who give written consent to participate in this study
Exclusion Criteria
- •1\) Patients with mimic HFpEF: Decompensated heart failure, history of EF less than 40%, pulmonary arterial hypertension, more than mild aortic or mitral valve stenosis, more than moderate aortic or mitral valve regurgitation, cardiomyopathy, acute coronary syndrome, complex adult congenital heart disease
- •2\) Subjects who cannot keep cycle ergometry exercise (0 watts) for more than 30 seconds
- •3\) Patients who are judged to be unsuitable for the study by the investigators
Outcomes
Primary Outcomes
Not specified
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