Compare effect of furosemide inhalation versus placebo in patients with acute cardiogenic pulmonary edema
Phase 3
Recruiting
- Conditions
- Acute pulmonary oedema.Left ventricular failure
- Registration Number
- IRCT2017101436753N1
- Lead Sponsor
- Vice chancellor for research, Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
All the patients with acute cardiogenic edema will be included in the study.
Exclusion criteria: not willing to participate in the study, history of susceptibility to sulfa drugs, unstable hemodynamics; requiring mechanical ventilation; decreased consciousness, accompany with another illness requiring treatment in the first 10 minutes of treatment with digoxin, beta blocker, beta-agonist and calcium; need to have another inhaling treatment in the first 10 minutes and need to have non-invasive ventilation.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oxygen saturation. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Pulse oximeter.;Respiratory rate. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Number of breaths per minute.;Heart rate. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Heart beats at per minute.;Arterial blood gases. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Arterial blood gases test.;Dyspnea Severity. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: MMRC Dyspnea Severity Scale.
- Secondary Outcome Measures
Name Time Method Crackles. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Stethoscope.;Wheezing. Timepoint: Baseline and 10 minutes after intervention. Method of measurement: Stethoscope.