NCT00415688已完成4 期
A Randomized, Controlled Trial of a Low-Carbohydrate, Ketogenic Diet Versus a Low-Glycemic Index Diet for Obesity-Related Type 2 Diabetes
Robert C. Atkins Foundation2 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2004年7月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Hemoglobin A1c
研究概览
简要总结
Dietary carbohydrate is the major determinant of postprandial glucose levels, and preliminary evidence suggests that low carbohydrate diets improve glycemic control when accompanied by weight loss. To determine if glycemic control can be improved by varying dietary carbohydrate during weight loss, we compared two weight loss diets with different carbohydrate levels for the treatment of obesity-related type 2 diabetes over 24 weeks in the outpatient setting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •type 2 diabetes mellitus for at least one year
- •hgba1c > 6.0
- •BMI from 27-50 kg/m2
排除标准
- •Unstable medical condition
- •Serious medical condition
- •AST or ALT > 100
- •Serum creatinine > 1.5
结局指标
主要结局
Hemoglobin A1c
次要结局
- Body weight
- Serum lipoproteins
研究者
研究点 (2)
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