Aerobic Interval Training Reduces and Compensates Age Related Decline in Cardiac Function
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diastolic Dysfunction
- Sponsor
- Norwegian University of Science and Technology
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years. The old sedate cohort will be compared to young, sedate subjects also performing aerobic interval training and old master athletes without intervention.
Detailed Description
Aging is associated with a reduced diastolic and systolic function of the heart. Earlier studies have shown that physical exercise can improve both systolic and diastolic function. However the impact on age-related cardiac function is to some extent conflicting. The use of different training intensities will impact on the cardiac result. We have in earlier studies shown aerobic interval training at 90 % of maximal heart rate (4x4 minutes) to have more impact on cardiac function, endothelial function and maximal oxygen uptake compared to moderate intensity. To our knowledge the effect of aerobic interval training on cardiac function has not been studied in an old, sedate group before.
Investigators
Eligibility Criteria
Inclusion Criteria
- •over 70 years, healthy
- •not exercising more than twice per week
Exclusion Criteria
- •chronic illness
- •chronic use of any medication
- •regular smoking
- •metabolic or cardiovascular diseases
Outcomes
Primary Outcomes
Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.
Time Frame: 12 weeks
Secondary Outcomes
- Improvement of left and right ventricular systolic tissue velocity function at rest and sub maximal exercise, S'.(12weeks)