Effect of Exercise on Heart Function in Healthy Elderly People

Not Applicable

Completed

• Conditions: Diastolic Dysfunction
• Interventions: Other: Aerobic interval training

• Registration Number: NCT00804518
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years. The old sedate cohort will be compared to young, sedate subjects also performing aerobic interval training and old master athletes without intervention.

Detailed Description

Aging is associated with a reduced diastolic and systolic function of the heart. Earlier studies have shown that physical exercise can improve both systolic and diastolic function. However the impact on age-related cardiac function is to some extent conflicting. The use of different training intensities will impact on the cardiac result. We have in earlier studies shown aerobic interval training at 90 % of maximal heart rate (4x4 minutes) to have more impact on cardiac function, endothelial function and maximal oxygen uptake compared to moderate intensity.

To our knowledge the effect of aerobic interval training on cardiac function has not been studied in an old, sedate group before.

Study Timeline

• Study Start: 2008-11
• Study First Submitted: 2008-12-08
• Study First Submitted QC: 2008-12-08
• Study First Posted: 2008-12-09
• Primary Completion: 2009-03
• Study Completion: 2009-08
• Status Verified: 2016-07
• Last Update Submitted: 2016-07-15
• Last Update Posted: 2016-07-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• over 70 years, healthy
• not exercising more than twice per week

Exclusion Criteria

• chronic illness
• chronic use of any medication
• regular smoking
• metabolic or cardiovascular diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Exercise intervention	Aerobic interval training	-

Primary Outcome Measures

Name	Time	Method
Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.	12 weeks

Secondary Outcome Measures

Name	Time	Method
Improvement of left and right ventricular systolic tissue velocity function at rest and sub maximal exercise, S'.	12weeks

Trial Locations

Locations (1)

Ntnu/Dmf/Isb; 🇳🇴 Trondheim, Sør-Trøndelag, Norway