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Clinical Trials/NCT05489783
NCT05489783
Recruiting
Not Applicable

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

Memorial Sloan Kettering Cancer Center7 sites in 1 country50 target enrollmentJuly 29, 2022
ConditionsGlioma

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Glioma
Sponsor
Memorial Sloan Kettering Cancer Center
Enrollment
50
Locations
7
Primary Endpoint
Registry of patients with Neurofibromatosis Type 1 (NF1) associated glioma
Status
Recruiting
Last Updated
10 months ago

Overview

Brief Summary

This study will collect medical records, scan results, and complete surveys to create a registry about people with a neurofibromatosis type 1-associated brain tumor (NF1-associated glioma). A registry is a collection of health information about individuals, and it is usually focused on a specific diagnosis or condition.

This registry study will help the researchers learn more about the diagnosis, treatment, and quality of life of people with NF1-associated glioma. The researchers want to understand what happens as a result of different treatments for NF1-associated glioma and how these treatments and the disease itself affect people's lives over a period of time. Information collected during this study could affect how doctors diagnose, test, and treat NF1-associated glioma, and the study could help future patients with this type of cancer.

Registry
clinicaltrials.gov
Start Date
July 29, 2022
End Date
July 31, 2026
Last Updated
10 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis that meets NIH criteria for NF1 disease by either 1) documented clinical record establishing NF1 or 2) self-reported with supported documentation upon medical record collection.
  • Willing to have historical and future NF1 related health records sent to registry for review.
  • Radiologic or pathologically confirmed glioma.
  • Individuals ≥18 years of age on the date of informed consent.

Exclusion Criteria

  • Unwillingness to sign informed consent.
  • No proficiency in English or Spanish as determined by the Investigator.

Outcomes

Primary Outcomes

Registry of patients with Neurofibromatosis Type 1 (NF1) associated glioma

Time Frame: 5 years

The overarching goal of the registry is to collect baseline and follow-up 1) clinical and 2) imaging data to have a centralized and living repository of information about the adult glioma NF1 patient population.

Study Sites (7)

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