Adverse Drug Reactions With Fatal Outcome
Completed
- Conditions
- Adverse Drug Reaction
- Interventions
- Drug: adverse drug reaction
- Registration Number
- NCT02838212
- Lead Sponsor
- Germans Trias i Pujol Hospital
- Brief Summary
The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015
- Detailed Description
The investigators aimed to determine the incidence of drug-related mortality of admitted patients in a university hospital during the year 2015
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1135
Inclusion Criteria
- inpatients deaths and drug-related deaths.
Exclusion Criteria
- death patients in the emergency room, patients with a death diagnosis not available, and dead patients due to other causes non-drug related.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Drug-related deaths adverse drug reaction fatal adverse drug reactions
- Primary Outcome Measures
Name Time Method Incidence of drug-related deaths of all hospital admissions during the year 2015
- Secondary Outcome Measures
Name Time Method Number of drug-related deaths with autopsy during the year 2015 Number of drug-related deaths with the suspected drug started the previous week during the year 2015 Number of drug-related deaths with drug interactions between suspected drugs during the year 2015 Number of preventable drug-related deaths assessed by Schumock criteria during the year 2015 Number of drug-related deaths with polypharmacy during the year 2015 Polypharmacy: when patient received \>10 drugs
Incidence of drug-related deaths of all inpatients deaths during the year 2015. Number of drug-related deaths in which the suspected drug had a contributive role during the year 2015 Number of drug-related deaths with "certain" or "probable" categories assessed by World Health Organization (WHO) criteria and Naranjo algorithm during the year 2015 Risk factors of drug-related deaths during the year 2015 risk factors assessed: age, sex, Charlson score, and hospitalization length
Number of drug-related deaths presented during hospitalization during the year 2015