MedPath

Standardized cognitive training for MS patients

Completed
Conditions
Multiple Sclerosis (MS)
Nervous System Diseases
Registration Number
ISRCTN57222203
Lead Sponsor
German Federal Pension Insurance (Deutsche Rentenversicherung Bund)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
285
Inclusion Criteria

1. MS (McDonald-criteria (RRMS, PPMS, SPMS)
2. Expanded Disability Status Scale Score (EDSS) < 6.5)
3. Perceived neuropsychiatric deficits
4. Interest to participate
5. To be in a rehabilitation centre
6. Aged 18-80 years

Exclusion Criteria

1. Probable MS
2. Neuromyelitis Optica
3.SDMT < -2,5 SD

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Perceived cognitive deficits measured using the perceived deficit questionnaire (PDQ) at baseline, 3 weeks, 3, 6 and 12 months.
Secondary Outcome Measures
NameTimeMethod
1. Coping and self-efficacy are measured using the Coping Self Efficacy Scale (CSES) at baseline, 3 weeks, 3, 6 and 12 months<br>2. Fatigue is measured using the Fatigue Scale for Motor and Cognition (FSMC) at baseline, 3 weeks, 3, 6 and 12 months<br>3. Working Memory is measured using the Corsi-Block-Test / Digit Span backward (Wechsler Memory Scale revised) at baseline, 3 weeks, 3, 6 and 12 months
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