NL-OMON32321尚未招募不适用
The effect of the a7nACh receptor agonist GTS-21 on inflammation and end-organ dysfunction during human endotoxemia - Anti-inflammatory effects of GTS-21 after LPS
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 25 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •healthy male volunteers (no medical history, no medication)
- •age 18-35 years
- •non-smokers
排除标准
- •Use of any medication
- •History, signs or symptoms of cardiovascular disease
- •(Family) history of cerebrovascular disease
- •Previous vagal collaps
- •Hypertension (defined as RR systolic > 160 or RR diastolic > 90)
- •Hypotension (defined as RR systolic < 100 or RR diastolic < 50)
- •Renal impairement (defined as plasma creatinin >120 µmol/l)
- •Liver enzyme abnormalities or positive hepatitis serology
- •Positive HIV test
研究者
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