Randomized Study on Salt Intake and Energy Metabolism
- Conditions
- Healthy
- Registration Number
- NCT03024567
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
To perform a randomized, double-blind clinical study on the effects of an increased salt intake on metabolic, cardiovascular and immunological parameters and the gut microbiota
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Healthy men and women
- 18 - 50 years
- Body mass index 18.5 - 29.9 kg/m2
- Clinically relevant heart, lung, liver, and kidney diseases
- Current or chronic infection
- Habitual use of probiotics or dietary supplements
- Pregnancy, lactation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Dietary induced thermogenis (%) 14 days Decrease of dietary induced thermogenis after salt vs. placebo
- Secondary Outcome Measures
Name Time Method Gut microbiome 14 days Change of gut microbiome composition after salt vs. placebo
Systolic blood pressure (mmHg) 14 days Increase of systolic blood pressure after salt vs. placebo
Lymphocytic pro-inflammatory mediators 14 days Increase of lymphocytic pro-inflammatory mediators after salt vs. placebo
Related Research Topics
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Trial Locations
- Locations (1)
Experimental and Clinical Research Center
🇩🇪Berlin, Germany
Experimental and Clinical Research Center🇩🇪Berlin, Germany