Randomized controlled trial to evaluate clinical safety and efficacy of oral immunotherapy with low dose of egg for children with egg allergy
Not Applicable
- Conditions
- Food hypersensitivity,Food allergy
- Registration Number
- JPRN-UMIN000005073
- Lead Sponsor
- ational Center for Child Health and Development
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients without immediate-type reaction to egg 2)Patients with uncontrolled asthma, atopic dermatitis or urticaria 3)Corn allergy patients 4)Patients who have treatment history or plan with omalizumab
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The result of double -blind placebo controlled food challenge test of egg after 25-28 weeks intervention
- Secondary Outcome Measures
Name Time Method 1)The threshold change of egg allergen dose to provoke immediate reaction before and after this intervention 2)The change of egg specific antibody serum concentration before and after this intervention 3)Incidence of patients who experience allergic reaction due to adverse effect of this intervention 4)Onset number of allergic reaction due to adverse effect of this intervention in each case