Pain relieving strategies in chronic tension-type headache(CTTH)
- Conditions
- Health Condition 1: null- chronic tension type headache
- Registration Number
- CTRI/2016/10/007344
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
This study is a randomized, parallel group, placebo controlled trial to study the effect of transcranial
magnetic stimulation on pain modulation status in chronic tension-type headache patients. Primary outcomes will be
subjective and objectives assessment of pain, biochemical analysis before and after rTMS therapywhich will be given for four weeks/five consecutive days/week.
Use of morphinomimetic drugs,Use of muscle relaxants H/o drug addiction H/o Hormonal therapy H/o vasodilator drugs H/o other pain relieving measure like yoga, acupuncture, acupressure etc. H/o ferromagnetic implants in head and neck regions, cardiac pacemakers H/o abnormal menstrual cycle, pregnancy, lactation
H/o seizure
H/o diabetes
H/o any peripheral neuropathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Decrease in VAS Pain rating by 50% <br/ ><br>2.Improvement decrease in LH level in response to sucrose <br/ ><br>challenge test which is deranged in CTTH patients <br/ ><br>3.The improvement nociceptive flexion reflex/R-III thresholdTimepoint: The assessment will be done at the beginning of the treatment and after the completion of 20 days of rTMS therapy
- Secondary Outcome Measures
Name Time Method Pain in CTTH is mediated by opioids <br/ ><br>rTMS is effective therapy for treatment of CTTH <br/ ><br>Timepoint: Outcome name:Oral sucrose challenge test, <br/ ><br>25gm/100 ml, pre and post rTMS, Time points:6 <br/ ><br>months, 1 year <br/ ><br>Outcome name: rTMS, 30 min/day/20 sessions, <br/ ><br>Time points:4 weeks