2024-511890-30-03招募中4 期
Frozen-thawed embryo transfer in a natural versus artificial cycle: a randomized clinical trial.
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- UZ Leuven
- 入组人数
- 554
- 试验地点
- 5
- 主要终点
- Clinical pregnancy rate with fetal heart beat
研究概览
简要总结
Finding the optimal endometrial preparation protocol for transfer of a frozen-thawed embryo
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 64 years（18-64 Years）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women undergoing FET after a first, second or third fresh IVF/ICSI cycle
- •Single embryo transfer (SET) or Double embryo transfer (DET)
- •Female age between 18-45 year
- •Women having a natural ovulatory cycle (24-35 days)
- •Normal uterine cavity (fundal indentation at the cavity <10mm)
- •Written informed consent
排除标准
- •Use of donor gametes
- •BMI > or equal to 35 kg / m2
- •Any contra-indication to estrogen or progesterone supplementation (e.g. history of thrombosis, prior or current hormone-sensitive malignancy…)
结局指标
主要结局
Clinical pregnancy rate with fetal heart beat
Clinical pregnancy rate with fetal heart beat
次要结局
- Biochemical pregnancy rate, miscarriage rate, ectopic pregnancy rate, live birth rate, multiple pregnancy rate, adverse events, cycle cancellation rate, endometrial thickness, endometrial pattern, number of center visits to monitor FET cycle, cost analysis per cycle, patient satisfaction
- Obstetrical outcomes in case of pregnancy: gestational age, birth weight, incidence of pregnancy- induced hypertension, pre-eclampsia, placenta previa, placenta accrete/increta/percreta, abruptio placentae, postpartum hemorrhage (early, late)
研究者
Joke De Roover
Scientific
UZ Leuven
研究点 (5)
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