Effects of an exercise program and a lifestyle app on sleep parameters, body composition, physical fitness and neurocognitive function in overweight and obese patients (aged 18-50 years) diagnostic of mild sleep disorders of breathing

Horizon 2020 - European Union0 sites200 target enrollmentFebruary 9, 2023

Overview

No summary available.

Registry

who.int

Start Date

February 9, 2023

End Date

December 31, 2023

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Horizon 2020 - European Union

•1\. Signed, informed, written consent
•2\. Age 18 \- 50 years
•3\. Verified mild to moderate sleep\-disordered\-breathing according to the current American Academy of Sleep Medicine and International Classification of Sleep Disorders criteria
•4\. The SDB level may range from habitual snoring to positional and mild obstructive sleep apnea, not fulfilling the criteria for continuous positive airway pressure therapy treatment
•5\. BMI \=25 kg/m2 (overweight or obese)
•6\. Inactive person (no participation in exercise programs at baseline)
•7\. Subjects willing to try lifestyle change, including an exercise program
•8\. Willingness to perform the study\-specific testing both at baseline and during follow\-up
•9\. Ability to read, follow the lifestyle program and answer the questionnaires in DMP, electronic sleep diary and objective daytime testing (via DMP and physical visits)

•1\. Severe OSA
•2\. Inability to perform an exercise
•3\. Regular use of hypnotic medications
•4\. Clinically verified dominant central sleep apnea
•5\. Known history of active malignant disease
•6\. Blindness or hearing loss
•7\. Unstable cardiometabolic disease
•8\. Unstable psychiatric disease
•9\. Ongoing alcohol or drug abuse
•10\. Other medical conditions which may interfere with the study protocol in the opinion of the investigator