A feasibility study of adjuvant therapy with FOLFOX plus Ca/Mg for the patient with colorectal cancer
- Conditions
- Colorectal Cancer
- Registration Number
- JPRN-UMIN000003708
- Lead Sponsor
- Kyushu Study group of Clinical Cancer
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 48
Not provided
1.Patients who had received blood transfusion, blood products, or hematopoietic growth factors such as granulocyte-colony stimulating factor within 7 days prior to registration. 2.History of the severe hypersensitivity. 3.Sensory neuropathy. 4.Active other malignancies. 5.Active infection 6.History of mental disorder,central nerve disorder. 7.Watery stools or Grade 2 or more diarrhea 8.Requiring steroid drug 9.Pregnant or lactating woman 10.Co-mobility, such as interstitial lung disease, lung fibrosis, intestinal paralysis, ileus,uncontrolled diabetes, liver cirrhosis, viral hepatitis type B ,kidney failure, uncontrolled hypertension, history of cardiac infarction 11.History of the internal organ transplant 12.Hypercalcemia ,renal calculus 13.Requiring cardiac glycoside 14.High probability of recurrence 15.Not appropriate for the study at the physician's assessment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the rate of completion of treatment as planned
- Secondary Outcome Measures
Name Time Method Safety (especially peripheral neuropathy, digestive symptom ) Quality of life Disease free survival Overall survival