Gender-specific differences in perioperative management and early postoperative and long-term oncosurgical outcome in gastric cancer in a prospective multicenter observational study

• Conditions: C16.0; C16.1; C16.2; C16.3; C16.4; C16.5; C16.6; C16.8; C16.9; Cardia

• Registration Number: DRKS00031968
• Lead Sponsor: oUniversitätsklinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie; Universitätsklinikum Magdeburg A. ö. R

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-09-30
• Study Start: 2023-07-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 2897

Inclusion Criteria

histologically confirmed, primary gastric carcinoma - patients with carcinoma of the esophagogastric junction (AEG type I, II, III), corpus-fundus, antrum, pylorus, gastric stump and early gastric carcinoma were included.

Exclusion Criteria

patients
- in T1-secured primary gastric carcinoma only an endoscopic intervention
have experienced
- who have received only chemotherapeutic treatment
- who already have a history of gastric carcinoma
* a previous operation or
* have undergone a recurrence operation during the study period and
*were exclusively treated with interventional endoscopy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
gender difference in:<br>- early postoperative outcome, characterized by morbidity and mortality;<br>- Long-term oncosurgical outcome, characterized by 5-year (5-y)<br> overall survival, 5-year tumor-free survival and 5-year local recurrence rate,<br>in primary surgically treated gastric carcinoma

Secondary Outcome Measures

Name	Time	Method
- Significant influencing factors on outcome parameters: patient, tumor findings,<br> treatment-related<br>- Period comparison of the surgical-operative treatment results