Attentional Bias Modification Treatment in OCD

Not Applicable

Completed

• Conditions: Obsessive-compulsive Disorder
• Interventions: Behavioral: attentional bias modification treatment

• Registration Number: NCT02014194
• Lead Sponsor: Roseli Shavitt

Brief Summary

Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11
• Study First Submitted: 2013-11-25
• Study First Submitted QC: 2013-12-17
• Study First Posted: 2013-12-18
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-23
• Last Update Posted: 2018-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 30 patients with obsessive-compulsive diagnosis according to DSM-V (with cleaning and or symmetry dimensions)

• 30 health controls

Exclusion Criteria

• doing any kind of behavioral therapy in the moment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
attentional bias modification, placebo	attentional bias modification treatment	Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms). There are two arms with 15 OCD patients each one.
attentional bias modification, active group	attentional bias modification treatment	Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms).

Primary Outcome Measures

Name	Time	Method
Percentage of reduction of attentional bias	Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10.

Secondary Outcome Measures

Name	Time	Method
Reduction of anxiety symptoms	Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks)

Trial Locations

Locations (1)

University of Sao Paulo Medical School; 🇧🇷 Sao Paulo, Brazil