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Visualization of diffusion tensor imaging in acupuncture treatment of children with autism

Phase 1
Recruiting
Conditions
autism spectrum disorder
Registration Number
ITMCTR2100004963
Lead Sponsor
The First Affiliated Hospital of He'nan University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1.Patients meet TCM diagnostic criteria and DSM-5 diagnostic criteria;
2.Children with Autism Rating Scale (CARS) score > 30;
3.Aged 2 to 6 years;
4.The family members or guardians have informed consent to accept the established treatment plan and requirements (time, frequency, etc.).

Exclusion Criteria

1.People with Asperger syndrome, Rett syndrome, Heller syndrome and children with disruptive mental disorder were excluded;
2.People with acute or chronic infectious diseases;
3.Children with serious primary diseases such as heart, brain, liver, kidney and hematopoietic system;
4.Children with ADHD, Tourette Syndrome and other behavioral disorders, mental retardation and schizophrenia;
5.Patients with hearing impairment and patients with frequent epilepsy;
6.Strong resistance, continuous crying, unable to cooperate with the treatment of children;
7.Children who are delirious, behave strangely or cannot be controlled, and are prone to medical accidents during the acupuncture process;
8.Children participating in other clinical trials;
9.Bleeding tendency;
10.MRI examination is contraindicated.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Childhood Autism Rating Scale (CARS);Diffusion tensor imaging of nerve fiber bundles;Neuroelectrophysiological test;Autism Efficacy Assessment Scale (AETC);Behavioral Scale for Children with Autism (ABC);
Secondary Outcome Measures
NameTimeMethod
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