NCT03244969撤回不适用
Study of the Granulation Tissue Formation in the Early Fracture Hematoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Granulation tissue formation
研究概览
简要总结
The aim of the research is to identify structural tissue changes in the early fracture hematomas.
详细描述
The fracture hematomas obtained during reconstructive bone surgery from patients with bone fractures will be examined. Histological methods and ultra-thin sections for electron microscopy will be used to identify structural tissue changes in the granulation tissue in different period of time after bone fracture. Immunohistochemical analysis will be performed to estimate the dynamic of proliferation, differentiation and cell migration during granulation and reticulofibrosis bone tissues development.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 84 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with fractures of the upper and lower extremities
- •Patients for whom the surgical bone reconstruction are indicated
排除标准
- 未提供
结局指标
主要结局
Granulation tissue formation
时间窗: 23 days
次要结局
未报告次要终点
研究者
Mikhail Mavlikeev
aspirant of the morphology department
Kazan Federal University
研究点 (1)
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