Bone Healing Study
Withdrawn
- Conditions
- Bone Fracture
- Registration Number
- NCT03244969
- Lead Sponsor
- Kazan Federal University
- Brief Summary
The aim of the research is to identify structural tissue changes in the early fracture hematomas.
- Detailed Description
The fracture hematomas obtained during reconstructive bone surgery from patients with bone fractures will be examined. Histological methods and ultra-thin sections for electron microscopy will be used to identify structural tissue changes in the granulation tissue in different period of time after bone fracture. Immunohistochemical analysis will be performed to estimate the dynamic of proliferation, differentiation and cell migration during granulation and reticulofibrosis bone tissues development.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients with fractures of the upper and lower extremities
- Patients for whom the surgical bone reconstruction are indicated
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Granulation tissue formation 23 days
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Igor Plaksa
🇷🇺Moscow, Russian Federation