Comparing crocin and misoprostol effects on cervical ripening

Phase 3

Recruiting

• Conditions: Condition 1: Uterine polyp. Condition 2: endometrial hyperplasia. Condition 3: submucosal fibroid. Condition 4: Abnormal uterine bleeding. Condition 5: excessive bleeding in the premenopausal period.; Polyp of corpus uteri; Endometrial glandular hyperplasia; Submucous leiomyoma of uterus

• Registration Number: IRCT20150909023949N9
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

All women who are scheduled for operative hysteroscopy
No history of allergy to saffron or prostaglandins
Having written informed consent

Exclusion Criteria

Suffering from active hepatic, renal, hematologic or cardiologic disorder
Approved known malignancy of genital tract
Approved cervical insufficiency

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Size of the largest dilator passed from cervical canal without resistance. Timepoint: After the induction of the anesthesia and before entering the hysteroscope in the operating room. Method of measurement: examination performed by the surgeon- Using standard dilators in the operating room.

Secondary Outcome Measures

Name	Time	Method
The extent of cervical tissue softening. Timepoint: After induction of anesthesia and before entering the hysteroscope in the operating room. Method of measurement: examination by the surgeon in the operating room.;The length of time of the procedure till entering the uterine cavity. Timepoint: After induction of anesthesia in the operating room. Method of measurement: Using chronometer by the surgeon's assistant.