Combination of Canagliflozin with reduced dose of Sulfonylurea in Japanese type2 diabetic patients
Not Applicable
- Conditions
- type2 diabetes
- Registration Number
- JPRN-UMIN000022718
- Lead Sponsor
- Yodogawa Christian Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
estimated glomerular filtration rate (eGFR) <45 ml/min/1.73 m2 (using the MDRD equation); acute coronary syndrome, stroke, or transient ischemic attack within 3 months prior to consent; severe liver dysfunction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HbA1c, glycoalbumin, FPG, and daily profile of blood glucose and glycemic variability evaluated by CGMs
- Secondary Outcome Measures
Name Time Method weight, systolic BP, diastolic BP, HOMA-R, HOMA-beta, fasting CPR index, LDL-cholestrrol , HDL-cholestrrol, triglyceride, free fatty acid, hematocrit, creatinine, uric acid, urine ketone body, blood ketone body, urinary sediment, and CRP