Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
Recruiting
- Conditions
- Traumatic Brain Injury
- Registration Number
- NCT05084352
- Lead Sponsor
- University of Maryland, Baltimore
- Brief Summary
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1200
Inclusion Criteria
- Arrival to the hospital within 6 hours of injury
- Age >= 18 years old
- Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings.
Exclusion Criteria
- Deemed to have a non-survivable TBI
- Brain dead on arrival
- Active substance abuse for opiates and cocaine as noted by admission toxicology screen.
- Any thoracic or abdominal injury resulting in open surgical intervention
- Pregnancy
- Prisoners
- Active military
- Non - English speaking (due to necessity for consent in aims 2 and 3)
- Age > 89 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Neurological Decline First 48 hours of injury Neurological decline is defined as a worsening in neurological status determined by a 2 point decline GCS, pupillary change, radiographic worsening defined by Rotterdam score, need for neurological or neurosurgical intervention (eg. treatment of seizure, raised ICP, hematoma evacuation)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Maryland Medical Center
🇺🇸Baltimore, Maryland, United States