A clinical trial to study the role of increased serum total bilirubin level as a new tool to detect complicated appendicitis.

Not Applicable

Conditions: Health Condition 1: K353- Acute appendicitis with localizedperitonitis

Registration Number: CTRI/2019/05/018879

Lead Sponsor: Bankura Sammilani Medical College and hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

All the cases of clinically diagnosed acute appendicitis of age 5 years and above scheduled for appendectomy at emergency surgical unit of this hospital, will be taken for study.Diagnosis will be confirmed by histopathological examination.

Exclusion Criteria

a.Patients of age below 5 years

b.Patients with appendicular lump fromation

c.All patients documented to have a past history of

i.Jaundice or Liver disease with hyperbilirubinaemia

ii.Chronic alcoholism (i.e. intake of alcohol of >40g/day for Men and >20g/day in Women for 10 years24)

iii.Hemolytic disease

iv.Acquired or Congenital biliary disease.

d.Patients with positive HbsAg and/or with recent history of jaundice.

e.Patients with history of gastro intestinal malignancy.

f.History of hepatotoxic drug use â?? past/recent.

g.All patients with cholelithiasis

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In this study, significantly elevated serum total bilirubin level(1.0 mg/dl) may be observed in majority of cases with complicated(i.e gangrenous/perforative) appendicitis than those with simple appendicitis and the bilirubinaemia will be mixed type (both direct and indirect bilirubin will be elevated).Timepoint: 12 Months

Secondary Outcome Measures