Effect of Licorice extracts in the treatment of Melasma

Phase 3

Conditions: Melasma or Chloasma.
Other disorders of pigmentation

Registration Number: IRCT2016040316016N2

Lead Sponsor: Kerman University of Medical Sciences, Deputy of research and technology

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 44

Inclusion Criteria

1- Patients with melasma clinically diagnosed 2- Women patients 3- Age between 20 to 40 years old 4- Patients with one lesion at least 5- Those don,t use any treatment for melasma during the six months prior to commencement of the study. Exclusion criteria: 1- Pregnant women 2- Lactating women 3- Those under treatment with other drugs for melasma during the six months prior to commencement of the study 4- Patients with history of allergy to licorice extracts 5- Treatment with oral contraceptives during of the study 6- Those under treatment with any drug for other diseases.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Size of lesions. Timepoint: Before and after intervention. Method of measurement: Examination.;Number of lesions. Timepoint: Before and after intervention. Method of measurement: Examination.;Location of lesions. Timepoint: Before intervention. Method of measurement: Examination.;Quality of life. Timepoint: Before and after intervention. Method of measurement: Questionare MELASQOL and DLQI.;Response to treatment. Timepoint: Before intervention and then at 4, 8 and 12 weeks. Method of measurement: Examination.;Course of the disease. Timepoint: Before intervention. Method of measurement: Questionare.;Wood,s lamp examination. Timepoint: Before intervention. Method of measurement: Examination.

Secondary Outcome Measures