Skip to main content
Clinical Trials/NCT07551323
NCT07551323
Not yet recruiting
Not Applicable

Comparison of the Effectiveness of Myofascial Release Technique and Pilates Exercises in Chronic Non-Specific Low Back Pain

Bahçeşehir University1 site in 1 country30 target enrollmentStarted: April 10, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Bahçeşehir University
Enrollment
30
Locations
1
Primary Endpoint
Pain Intensity (VAS)

Overview

Brief Summary

Objective:

To evaluate the effectiveness of adding Myofascial Release Technique (MRT) to Clinical Pilates in adults with chronic non-specific low back pain (CNSLBP).

Hypothesis:

MRT combined with Pilates will lead to greater improvements in pain, functional disability, and soft tissue mobility compared to Pilates alone.

Design & Intervention:

Randomized controlled trial. Participants (18-45 years) will be randomly assigned to:

MRT + Clinical Pilates Clinical Pilates only for 6 weeks (2 sessions/week).

Outcomes:

Primary: Pain (VAS), ultrasonographic thickness (multifidus & thoracolumbar fascia) Secondary: Disability (ODI), lumbar mobility, balance

Eligibility:

Adults with CNSLBP ≥3 months; excluding spinal surgery, rheumatic disease, and pregnancy.

Detailed Description

Rationale Chronic non-specific low back pain (CNSLBP) is associated with structural changes in the thoracolumbar fascia (TLF) and atrophy of the multifidus muscle. While Clinical Pilates enhances core stability, it may not adequately address myofascial densification. This study evaluates whether adding Myofascial Release Technique (MRT) to a Pilates program provides superior improvements in tissue morphology (TLF and multifidus thickness) and clinical outcomes compared to Pilates alone.

Intervention Protocol

A 6-week supervised program (2 sessions/week) will be conducted:

Experimental Group: 20 minutes of manual MRT applied to the thoracolumbar region followed by a standardized Clinical Pilates session focusing on lumbopelvic stabilization.

Control Group: Clinical Pilates program only (Core stabilization exercises: pelvic curls, bird-dog, planks).

Ultrasonographic Assessment

High-resolution musculoskeletal ultrasound will be used for objective analysis at the L3, L4, and L5 vertebral levels (2 cm lateral to the spinous processes):

TLF Thickness: Measurement of the posterior layer of the thoracolumbar fascia.

Multifidus Muscle Thickness: Quantitative measurement of the multifidus muscle thickness and potential hypertrophy post-intervention.

All measurements will be performed by a blinded assessor to ensure the objectivity of the data.

Statistical Plan Comparison: Intra-group changes will be analyzed with Paired t-tests, and inter-group differences with Independent t-tests.

Correlation: Pearson/Spearman tests will assess the relationship between ultrasonographic changes (TLF and multifidus thickness) and clinical improvements (VAS/ODI).

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 45 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Chronic non-specific low back pain lasting at least 3 months No clinical signs of nerve root compression or neurological deficit Aged 18-45 years No physical therapy or manual therapy for low back pain in the last 1 month Pain intensity of at least 3 on the Visual Analog Scale (VAS) in the last week Willingness to participate and written informed consent

Exclusion Criteria

  • Systemic, neurological, or orthopedic conditions limiting exercise participation Lumbar radiculopathy or severe spinal pathology (e.g., disc herniation with nerve root compression) History of lumbar spine surgery Unhealed fracture or recent surgical intervention Rheumatologic or inflammatory diseases Neurological disorders affecting movement or balance Participation in any physiotherapy or rehabilitation program in the last 6 months Pregnancy or postpartum period within the last 6 months

Arms & Interventions

Sham MRT + Clinical Pilates

Sham Comparator

Participants in this group will receive sham myofascial release technique combined with Clinical Pilates exercises. The sham intervention will involve light manual contact without sufficient pressure or technique to produce therapeutic effects. The Clinical Pilates program will be based on core stabilization principles and applied for 6 weeks, 2 sessions per week.

Intervention: Sham Myofascial Release Technique (Other)

Sham MRT + Clinical Pilates

Sham Comparator

Participants in this group will receive sham myofascial release technique combined with Clinical Pilates exercises. The sham intervention will involve light manual contact without sufficient pressure or technique to produce therapeutic effects. The Clinical Pilates program will be based on core stabilization principles and applied for 6 weeks, 2 sessions per week.

Intervention: Clinical Pilates Exercise (Other)

MRT + Clinical Pilates

Experimental

Participants in this group will receive Myofascial Release Technique (MRT) combined with a Clinical Pilates exercise program. MRT will be applied to the lumbar and thoracolumbar regions using manual techniques aimed at improving fascial mobility and reducing tissue restriction. The Clinical Pilates program will focus on core stabilization, postural control and flexibility. The intervention will be administered for 6 weeks, 2 sessions per week

Intervention: Myofascial Release Technique (MRT) (Other)

MRT + Clinical Pilates

Experimental

Participants in this group will receive Myofascial Release Technique (MRT) combined with a Clinical Pilates exercise program. MRT will be applied to the lumbar and thoracolumbar regions using manual techniques aimed at improving fascial mobility and reducing tissue restriction. The Clinical Pilates program will focus on core stabilization, postural control and flexibility. The intervention will be administered for 6 weeks, 2 sessions per week

Intervention: Clinical Pilates Exercise (Other)

Outcomes

Primary Outcomes

Pain Intensity (VAS)

Time Frame: Baseline and 6 weeks (post-intervention)

Pain intensity will be measured using a 10-cm Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst imaginable pain. Participants will mark their current pain level on the scale.

Multifidus and Thoracolumbar Fascia Thickness

Time Frame: Baseline and 6 weeks (post-intervention)

Muscle and fascia thickness will be measured using ultrasonography to evaluate changes in soft tissue properties in the lumbar region.

Secondary Outcomes

  • Functional Disability (Oswestry Disability Index - ODI)(Baseline and 6 weeks)
  • Lumbar Mobility (Modified Schober Test)(Baseline and 6 weeks)
  • Dynamic Balance (Y-Balance Test)(Baseline and 6 weeks)

Investigators

Sponsor
Bahçeşehir University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Zerrin Yilmaz

PhD.(C)

Bahçeşehir University

Study Sites (1)

Loading locations...

Similar Trials