Stromal Vascular Fraction (SVF) enriched lipofilling plus PRP for the treatment of the aging face.

Completed

Conditions: atrophy of the skin
Loss of skin quality
loss of volume
10040795

Registration Number: NL-OMON46886

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Trial ended prematurely

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 28

Inclusion Criteria

- Females
- Aged 35-60
- Stable normal BMI (20-25) (1 year stable between 20-25)

Exclusion Criteria

• Male
• Aged below 35 or above 60 years
• Surgical interventions of the face in the year prior to the date of surgery
• Any oncological event in the patients history
• A known psychiatric condition
• A known systemic disease that will impair wound healing (e.g. diabetes mellitus, known atherosclerosis with an event that required hospitalization, collagen diseases, diseases of the skin).
• Smoking
• 20• Pregnancy or active child wish
• Frequent exposure to known carcinogenic substances (e.g. work related).
• Active or previous use of hormone replacement therapy.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Postoperative skin quality measured with a Multi Probe Adapter system (Courage<br /><br>Khanza Colone Germany) containing two skin measurement probes (Cutometer<br /><br>MPA580: Mechanical parameters of the skin and Tewameter TM300: Skin barrier<br /><br>function and transepidermal waterloss,) on predetermined fixed positions in the<br /><br>face on predetermined times (preoperative, 6 weeks, 3 months, 6 months and 1<br /><br>year postoperative). </p><br>

Secondary Outcome Measures