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Clinical Trials/NCT02320201
NCT02320201
Withdrawn
N/A

Foot Neuromodulation for Overactive Bladder in Children

Rajeev Chaudhry1 site in 1 countrySeptember 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
Overactive Bladder
Sponsor
Rajeev Chaudhry
Locations
1
Primary Endpoint
Number of participants with decreased urinary frequency
Status
Withdrawn
Last Updated
3 years ago

Overview

Brief Summary

To determine the effects of electrical stimulation of the nerves in the foot on overactive bladder conditions in children.

Detailed Description

Bladder overactivity in the pediatric population presents a more challenging clinical situation than in adults after failure of medical therapy, as other treatments with proven efficacy such as botulinum injections and interstim sacral nerve stimulators are too invasive for the routine use in children. A non-invasive, effective way to improve overactive bladder in this population would have a great impact on a child's quality of life.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
December 2020
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor Investigator
Principal Investigator

Rajeev Chaudhry

Assistant Professor

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Children ages 5 to 16 years old without any specific neurological disorder or urinary tract infection, clinically diagnosed as idiopathic over active bladder (OAB)
  • Currently having OAB symptoms, i.e. urinary frequency, urgency, or incontinence
  • Having been assessed for and treated if applicable for behavioral etiologies of OAB - holding urine too long, consuming excess caffeine or other bladder irritants.
  • Having been assessed for and treated if applicable for constipation

Exclusion Criteria

  • Patients with known neurological disorders which may be contributing to OAB symptoms
  • Patients found through history to have significant behavioral causes of OAB including consumption of known bladder irritants and dysfunctional voiding.
  • Patients with chronic constipation who are non-compliant with previous pharmacologic efforts to treat.
  • Patients who are not adequately potty trained
  • Patients who do not tolerate initial stimulation training session in the urology clinic upon enrollment
  • Children with any implantable medical devices such as a pacemaker will be excluded from the study
  • Note: Any patient currently taking medication such as an anti-muscarinic or a tricyclic antidepressant for overactive bladder at time of enrollment will be eligible to participate and will be continued on their usual medication and dosage throughout the study.

Outcomes

Primary Outcomes

Number of participants with decreased urinary frequency

Time Frame: 3 weeks

Foot stimulation decreases urinary frequency measured by a daily voiding diary.

Secondary Outcomes

  • Number of participants with improved over active bladder symptoms(3 weeks)

Study Sites (1)

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