Is Preoperative Pain Response Upon Tonic Heat Stimulation Predictive for Pain After Total Knee Arthroplasty?
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain, Postoperative
- Sponsor
- Hvidovre University Hospital
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Cumulated pain (from 0-24 hours after surgery)
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
In this consecutive, prospective cohort study trial the investigators evaluate if preoperative pain response upon heat stimulation is predictive for acute and subacute postoperative pain after total knee arthroplasty.
Detailed Description
The preoperative heat stimulation consists of short and long tonic heat stimulation. Pain response is evaluated with an electronic visual analog scale. Furthermore the investigators evaluate other factors possibly predictable for acute and subacute postoperative pain after total knee arthroplasty - demographic factors, preoperative pain related factors, psychosocial factors (Hospital Anxiety and Depression Scale and Pain Catastrophizing Scale).
Investigators
Troels Haxholdt Lunn
MD
Hvidovre University Hospital
Eligibility Criteria
Inclusion Criteria
- •Ethnic danes, above 18 years and able to give informed consent scheduled for primary, unilateral total knee arthroplasty.
Exclusion Criteria
- •Bilateral / revision arthroplasty
- •Disease affection central or peripheral nerve function
- •Alcohol and medical abuse
- •Daily use of opioids or glucocorticoids
- •Malignancy
- •BMI \> 40
- •Depression
- •Dementia or other cognitive dysfunction
Outcomes
Primary Outcomes
Cumulated pain (from 0-24 hours after surgery)
Time Frame: 24 hours
Pain during walk 5 m (VAS)
Secondary Outcomes
- Cumulated pain (from day 1 to day 7 after surgery)(7 days)
- Pain at day 14 after surgery(14 days)
- Pain at day 30 after surgery(30 days)