A New Method for Evaluating Oxidative Stress in Behçet Disease: Thiol/Disulfide Homeostasis

Not Applicable

Active, not recruiting

• Conditions: Active Behcet DiseaseInactive Behcet Disease; oxidative stress; Behçet disease, thiol, disulfide&#44

• Registration Number: TCTR20200201003
• Lead Sponsor: Self sponsor

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-01
• Study Completion: 2020-02-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Participants in OABD and OIBD groups were followed up or recently diagnosed by the Ophthalmology Department of Fırat University College of Medicine. Likewise, sex and age matched healthy participants were also included as controls

Exclusion Criteria

systemic administration of steroids or immunosuppressive agents within the last 30 days, presence of another disease increasing oxidative stress state, alcohol abuse, ingestion of vitamin or another medicine having an oxidative effect in the previous six months, body mass index higher than 30 kg/m2, end stage BD, and intense cataract that restricted the examination of fundus.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma thiol/disulfide level At routine control novel spectrophotometric method was used for the assessment of plasma T/D homeostasis

Secondary Outcome Measures

Name	Time	Method
Total and native thiol, Disulfide At routine control novel spectrophotometric method