Relationship Between Bispectral Index (BIS) and Spectral Entropy (SpEn) During Desflurane Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- BIS index
研究概览
简要总结
The aim of this study was to estimate the relationship between BIS and Spectral Entropy values and any explicit or implicit memory or dreams recall during desflurane anaesthesia.
详细描述
During the last decade, an increasing number of monitor systems were developed designed to assess the depth of anesthesia.
Awareness is a rare occurrence of explicit recalls during anaesthesia with an incidence of 0,18% and the use of cerebral monitoring prevents about 50% of these events.
Different stages of awareness should be defined and implicit memorization is subconscious awareness without explicit recall and possible implicit recall with an incidence greater than awareness.
To assess implicit recalls, a large number of test can be used, for example the "word stem completation test" and the "free recall association test". These result easy to use and reliable in detect implicit memory.
Bispectral Index (BIS) and Spectral Entropy (SpEn) has been proposed, in recent years, as electroencephalographic monitors of anaesthesia depth.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 60 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •American society of anesthesiologist physical status I-II
- •Italian native speakers
排除标准
- •Psychiatric or neurologic diseases
- •Acoustic impairment
- •Obesity (Body Mass Index > 30)
- •Substance dependence.
结局指标
主要结局
BIS index
时间窗: change from baseline at 15 min
次要结局
- entropy values(24 h after emergency from anaesthesia)
研究者
Germano De Cosmo
PhD
Catholic University of the Sacred Heart
