A study to identify SARS-CoV-2 in erythrocytes of patients suffering from COVID-19 at an Apex tertiary care institute in Andhra Pradesh, South India.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Detection of COVID-19 RNA in RBC/Blood samples during active infection
研究概览
简要总结
The novel corona virus which started as an epidemic in Wuhan, China has become a pandemic affecting most countries in the world and infected a total of 53,04,772 people, with growing incidence rates of 1,00,264 patients every day, has caused deaths of 3,42,029 people across the globe as per World Health Organization (WHO). India, a developing country with the second largest population has reported a total of 1,38,845 people being infected and a total of 4,021 deaths due to novel corona virus pneumonia (COVID-19) as of 25th May 2020. There are studies that suggest that the novel COVID-19 disease can also attack 1-beta chain of haemoglobin and captures the porphyrin to inhibit human heme metabolism. In the present study, we would like to know whether SARS-CoV-2 has the capability to infect Erythrocytes. The effect of various modification on COVID-19 in blood will also be checked.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •COVID-19 Positive by RT-PCR.
排除标准
- •1.Negative for COVID-19 illness 2.Not willing to participate in the study 3.Age <18 years or >55 years 4.Prisoners 5.Pregnant women 6.Severely ill patients.
结局指标
主要结局
Detection of COVID-19 RNA in RBC/Blood samples during active infection
时间窗: immediately at enrolment considered Day1
次要结局
- DETECTION OF COVID-19 RNA IN RBC/BLOOD SAMPLES PLASMA OR LEUKOREDUCTION(AFTER CENTRIFUGATION)