Evaluation of the efficacy of proton pump inhibitor for postoperative delirium after hepatobiliary and pancreatic surgery
- Conditions
- Hepatectomy or pancreatectomy for diseases of the liver, biliary tract, pancreas, and duodenum
- Registration Number
- JPRN-jRCTs041220114
- Lead Sponsor
- Sugiura Teiichi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 82
1.Patients scheduled for elective hepatectomy or pancreatectomy for liver, biliary, pancreatic, and duodenal diseases
2.Age >= 70 years
3.Eastern Cooperative Oncology Group performance status of 0 or 1
4.Ability to undergo the Confusion Assessment Method-Intensive Care Unit (CAM-ICU)
5.Written informed consent
1.Patients scheduled for laparoscopic surgery.
2.Patients scheduled for hepatectomy combined with pancreatectomy.
3.Patients with dementia
4.Patients with a history of delirium
5.Patients diagnosed with psychological disorders such as alcoholism
6.Patients with habitual use of benzodiazepine receptor agonitst
7.Patients with habitual use of histamine H2-receptor antagonists within a week before registration
8.Patients with a history of hypersensitivity to proton pump inhibitor
9.Patients with habitual use of opioids or steroids
10.Patients who are determined not applicable for the study by the physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method