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Effect of preoperative Olanzapine on the incidence of postoperative nausea and vomiting

Not Applicable
Conditions
Health Condition 1: N72- Inflammatory disease of cervix uteriHealth Condition 2: N709- Salpingitis and oophoritis, unspecified
Registration Number
CTRI/2024/03/063683
Lead Sponsor
Dr Prasanta Kumar Das
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Gynecological patients undergoing laparoscopic surgeries

ASA 1 and 2

Exclusion Criteria

no consent, allergic to study drugs, renal and hepatic failure, on antiemetic and antipsychotic medications, prolonged qt interval, history of obstructive sleep apnea

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare the incidence of PONV in first 24 hours after surgery between two groupsTimepoint: To compare the incidence of PONV in first 24 hours after surgery between two groups
Secondary Outcome Measures
NameTimeMethod
Quality of recovery(QoR - 15)Timepoint: over 24 hours;requirement of rescue antiemetic (inj.Metoclopramide 10mg IV)Timepoint: 12 hours;severity of nausea and vomting by 4- point severity scaleTimepoint: over 24 hours;Side effects of OlanzapineTimepoint: over 24 hours
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