Effects of increased egg consumption as part of a weight-reducing diet on blood cholesterol and related biomarkers of coronary heart disease risk

Completed

• Conditions: Overweight; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN31221145
• Lead Sponsor: British Egg Information Service (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-10-05
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Healthy adult male and females aged 18-55 years
2. Body Mass Index (BMI) that classifies them as being overweight >25, <40

Exclusion Criteria

1. BMI >40 (morbid obesity)
2. Total plasma cholesterol >6.5 mM
3. No prescribed medication
4. No dietary supplements including 'cholesterol-lowering' foods (e.g. benecol or flora proactive) or existing diets or having lost >3 kg in preceding 2 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Total plasma cholesterol<br>2. Low-density lipoprotein (LDL) cholesterol<br>3. Body weight

Secondary Outcome Measures

Name	Time	Method
Plasma cholesterol precursors (mevalonate and lathosterol) and plant sterols (beta-sitosterol and campesterol) as markers of cholesterol synthesis and absorption respectively