Effectiveness of topical Insulin in Diabetic Foot Ulcer compared to normal saline dressing among inpatients of a tertiary health centre: A randomized control trial

all the consented participants will be admitted and would undergo the following investigations. Complete blood count, Fasting, postprandial blood sugar ,LFT , RFT , HbA1C , Doppler, X-ray , wound swab / pus culture sensitivity. Initial wound debridement (if needed) - removal of necrotic debris, slough, foreign body will be done. Patients will be selected by consecutive sampling , randomized into two groups by block randomization and allocation concealment will be done by SNOSE technique.Initial wound assessment will be done before randomization by the principle investigator. Both the groups will be started on empirical intravenous antibiotics (cefotaxime and metronidazole) which will be modified after the culture sensitivity reports, will receive same Diabetic diet from hospital, and their diabetic medications (such that blood glucose values are controlled).No intervention will be done for the systemic disease of the patient. Patients will be receiving daily dressing : test group will be receiving insulin dressing and the control group will be receiving normal saline dressing . The dressing solutions will be freshly prepared and opaque containers will be used. Periodical wound assessment will be done during the hospital stay using bates jenson wound assessment tool. Once the wound is healed or after two weeks (whichever is earlier) , the patient will be discharged.