Cross-sectional investigation of the characteristics of intestinal flora in patients with carotid atherosclerotic plaque ulcer

Not Applicable

Recruiting

• Conditions: Carotid atherosclerotic plaque ulcer

• Registration Number: ITMCTR2100005005
• Lead Sponsor: Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Exposure group:
Patients with carotid atherosclerotic plaque ulcer diagnosed by color Doppler ultrasound;
The patients with lumen stenosis < 75% were selected;
Subjects with at least one risk factor were hypertension or diabetes or hyperlipidemia.
The subjects aged from 40 to 70 were not limited in gender;
The patient informed consent and signed the informed consent form.
Non exposure group:
The patients with carotid atherosclerotic plaque but no ulcer were diagnosed by color Doppler ultrasound;
Patients with lumen stenosis less than 75%;
Subjects with at least one risk factor were hypertension or diabetes or hyperlipidemia.
The subjects aged from 40 to 70 were not limited in gender;
The patient informed consent and signed the informed consent form.

Exclusion Criteria

Exposure group:
Patients with acute stroke or myocardial infarction in recent 3 months were excluded;
Patients with severe arrhythmia, atrial fibrillation and heart failure were excluded;
Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system and respiratory system were excluded;
Patients with abnormal stool were excluded;
Patients who were taking antibiotics were excluded;
Pregnant women were excluded.

Non exposure group:
Patients with acute stroke or myocardial infarction in recent 3 months were excluded;
Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system and respiratory system were excluded;
Patients with abnormal stool were excluded;
Patients who were taking antibiotics were excluded;
Pregnant women were excluded.

Study & Design

• Study Type: Observational study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Distribution characteristics of TCM syndrome elements;Intestinal flora;

Secondary Outcome Measures

Name	Time	Method
Blood chemistry;Blood routine;