The Effect of Topical Tranexamic Acid in endoscopic sinus surgery
- Conditions
- Bleeding control and improvement of the quality of surgical field in sinus endoscopic surgery of those who need surgery that did not respond to drug therapy..Chronic sinusitis, unspecified
- Registration Number
- IRCT20180730040640N1
- Lead Sponsor
- Boushehr University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 56
Patients with chronic rhinosinusitis that don't not respond to drug therapy and require sinus surgery
The age of the participant(s) must be between 18 and 60 years old
The amount of hemoglobin of the participant should be above 10 g/dl
the amount of Bleeding time (BT), Prothrombin time (PT), Partial thromboplastin time (PTT), International normalized Ratio (INR) should be normal in participants.
Participants with cardiovascular disorders.
Participants who have coagulation disorders or who are taking anticoagulant medicines(drugs)
Participants with inherited coagulation disorders such as thrombophilia.
Participants with coagulation disorders history in the past.
Participants who have a history (record) of allergy to any drug(s) in the past.
Participants who have been suffering from renal deficiency in the past.
Participants with cirrhosis.
Participants with chronic diseases, such as diabetes and hypertension.
Participants who are pregnant.
participants with malignant nasal tumor.
Color blindness
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding during surgery. Timepoint: At 15th, 30th and 45th minute after intervention. Method of measurement: The Boezaart measuring scale.;Surgeon's satisfaction with quality of surgical field. Timepoint: At 15th, 30th and 45th minute after intervention. Method of measurement: Likert scale plan for satisfaction.
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: every 15 minutes after start of surgery. Method of measurement: heart monitoring.;Bleeding volume. Timepoint: every 15 minutes after start of surgery. Method of measurement: suction device.;Pulse rate. Timepoint: every 15 minutes after start of surgery. Method of measurement: heart monitoring.