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imited skin areas and vitamin D

Completed
Conditions
Topic: Dermatology
Subtopic: Skin (all Subtopics)
Disease: Dermatology
Skin and Connective Tissue Diseases
Registration Number
ISRCTN91255549
Lead Sponsor
niversity of Manchester
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

1. Healthy, ambulant, male and female adults aged 20-60 years
2. White Caucasian (sun-reactive skin type I-IV)
3. Willing and capable of participating to the extent and degree required by the protocol

Exclusion Criteria

1. Sunbathing or sunbed use in the last 3 months
2. Taking photoactive medication
3. Taking vitamin D, fish oil or calcium supplements
4. History of skin cancer or photosensitivity disorder
5. Pregnancy/lactation

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome measure is serum 25-hydroxyvitamin D (25(OH)D) concentration which is measured at baseline, then weekly up to 6 weeks. Further samples to be taken at weeks 8, 10 and 12. Serum 25(OH)D is measured by liquid chromatography tandem mass spectrophotometry (LC-MS/MS).
Secondary Outcome Measures
NameTimeMethod
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