imited skin areas and vitamin D
Completed
- Conditions
- Topic: DermatologySubtopic: Skin (all Subtopics)Disease: DermatologySkin and Connective Tissue Diseases
- Registration Number
- ISRCTN91255549
- Lead Sponsor
- niversity of Manchester
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Healthy, ambulant, male and female adults aged 20-60 years
2. White Caucasian (sun-reactive skin type I-IV)
3. Willing and capable of participating to the extent and degree required by the protocol
Exclusion Criteria
1. Sunbathing or sunbed use in the last 3 months
2. Taking photoactive medication
3. Taking vitamin D, fish oil or calcium supplements
4. History of skin cancer or photosensitivity disorder
5. Pregnancy/lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure is serum 25-hydroxyvitamin D (25(OH)D) concentration which is measured at baseline, then weekly up to 6 weeks. Further samples to be taken at weeks 8, 10 and 12. Serum 25(OH)D is measured by liquid chromatography tandem mass spectrophotometry (LC-MS/MS).
- Secondary Outcome Measures
Name Time Method