Perception of Blood Sugar Variations During Physical Activity in Healthy Subjects and Type 1 Diabetes Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 主要终点
- Feeling lucidity
研究概览
简要总结
Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity.
Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia.
Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.
详细描述
The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Type 1 diabetics diagnosed more than 3 years ago and controlled (an HbA1c of less than 8%) for "type 1 diabetes" group
- •without diabetes for "healkthy" group
- •Aged 18 to 65
- •Body Mass Index less than 30 kg/m2
- •regular running (at least 30 minutes per week and at least one 10-km run per year for the previous 2 years)
- •Agreeing to participate in the study
排除标准
- •Physical injury
- •beta blockers treatment
结局指标
主要结局
Feeling lucidity
时间窗: Day 0
Lucidity, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "not at all lucid" to "completely lucid"
Feeling fatigue
时间窗: Day 0
hydratation, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of dehydration" to "dehydrated"
blood sugar
时间窗: Day 0
Blood sugar evaluated in g/L via continuous blood glucose measurement
total running time
时间窗: Day 0
Sports performance evaluated by total running time of the 10 km run on a treadmill
average running speed
时间窗: Day 0
Sports performance evaluated by average running speed of the 10 km run on a treadmill
average speed per kilometer Sports performance
时间窗: Day 0
Sports performance evaluated by average speed per kilometer of the 10 km run on a treadmill
feeling hungry
时间窗: Day 0
hungry, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of hunger" to "hungry"
次要结局
未报告次要终点