Perception of Blood Sugar Variations During Physical Activity in Healthy Subjects and Type 1 Diabetes Patients
- Conditions
- Type 1 Diabetes
- Interventions
- Other: Physical activity
- Registration Number
- NCT05357534
- Lead Sponsor
- Université de Reims Champagne-Ardenne
- Brief Summary
Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity.
Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia.
Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.
- Detailed Description
The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 30
- Type 1 diabetics diagnosed more than 3 years ago and controlled (an HbA1c of less than 8%) for "type 1 diabetes" group
- without diabetes for "healkthy" group
- Male
- Aged 18 to 65
- Body Mass Index less than 30 kg/m2
- regular running (at least 30 minutes per week and at least one 10-km run per year for the previous 2 years)
- Agreeing to participate in the study
- Physical injury
- beta blockers treatment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description "Type 1 diabetes" group Physical activity "type 1 diabetes" group: patients with type 1 diabetes "healthy" group Physical activity "healthy" group : subjects without type 1 diabetes
- Primary Outcome Measures
Name Time Method average running speed Day 0 Sports performance evaluated by average running speed of the 10 km run on a treadmill
Feeling lucidity Day 0 Lucidity, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "not at all lucid" to "completely lucid"
Feeling fatigue Day 0 hydratation, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of dehydration" to "dehydrated"
blood sugar Day 0 Blood sugar evaluated in g/L via continuous blood glucose measurement
total running time Day 0 Sports performance evaluated by total running time of the 10 km run on a treadmill
feeling hungry Day 0 hungry, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of hunger" to "hungry"
average speed per kilometer Sports performance Day 0 Sports performance evaluated by average speed per kilometer of the 10 km run on a treadmill
- Secondary Outcome Measures
Name Time Method